Cargando…
Apatinib Inhibits the Invasion and Metastasis of Liver Cancer Cells by Downregulating MMP-Related Proteins via Regulation of the NF-κB Signaling Pathway
OBJECTIVE: We aimed to investigate whether apatinib has an inhibitory effect on the invasion and metastasis of liver cancer in vitro. METHODS: The anti-invasion and antimetastasis effects of apatinib in HepG2, Hep3B,Huh7 and SMMC-7721 liver cancer cell lines were tested by the wound-healing and tran...
Autores principales: | He, Xiaoxiao, Huang, Zaozao, Liu, Ping, Li, Qiuting, Wang, Mengmeng, Qiu, Mengjun, Xiong, Zhifan, Yang, Shengli |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322602/ https://www.ncbi.nlm.nih.gov/pubmed/32685465 http://dx.doi.org/10.1155/2020/3126182 |
Ejemplares similares
-
NF-κB inhibition is associated with OPN/MMP-9 downregulation in cutaneous melanoma
por: Guarneri, Claudio, et al.
Publicado: (2017) -
PinX1 inhibits the invasion and metastasis of human breast cancer via suppressing NF-κB/MMP-9 signaling pathway
por: Shi, Meilin, et al.
Publicado: (2015) -
Identification and Validation of the lncRNA BACE1-AS as Immune-Related Influencing Factor in Tumorigenesis following Pan-Carcinoma Analysis
por: Wang, Mengmeng, et al.
Publicado: (2021) -
TIPE-mediated up-regulation of MMP-9 promotes colorectal cancer invasion and metastasis through MKK-3/p38/NF-κB pro-oncogenic signaling pathway
por: Chen, Huiyu, et al.
Publicado: (2020) -
Nuclear HDAC6 inhibits invasion by suppressing NF-κB/MMP2 and is inversely correlated with metastasis of non-small cell lung cancer
por: Yang, Chih-Jen, et al.
Publicado: (2015)