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In silico and in vivo anti-malarial investigation on 1-(heteroaryl)-2-((5-nitroheteroaryl)methylene) hydrazine derivatives

BACKGROUND: Resistance of Plasmodium falciparum against common anti-malarial drugs emphasizes the need of alternative and more effective drugs. Synthetic derivatives of 1-(heteroaryl)-2-((5-nitroheteroaryl)methylene) hydrazine have showed in vitro anti-plasmodial activities. The present study aimed...

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Detalles Bibliográficos
Autores principales: Tahghighi, Azar, Mohamadi-Zarch, Seyed-Mahdi, Rahimi, Hamzeh, Marashiyan, Mahya, Maleki-Ravasan, Naseh, Eslamifar, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322848/
https://www.ncbi.nlm.nih.gov/pubmed/32600425
http://dx.doi.org/10.1186/s12936-020-03269-7