Wingless and Archipelago, a fly E3 ubiquitin ligase and a homolog of human tumor suppressor FBW7, show an antagonistic relationship in wing development

BACKGROUND: Archipelago (Ago) is a Drosophila homolog of mammalian F-box and WD repeat domain-containing 7 (FBW7, also known as FBXW7). In previous studies, FBW7 has been addressed as a tumor suppressor mediating ubiquitin-dependent proteolysis of several oncogenic proteins. Ubiquitination is a type...

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Detalles Bibliográficos
Autores principales: Nam, Sujin, Cho, Kyung-Ok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322864/
https://www.ncbi.nlm.nih.gov/pubmed/32594913
http://dx.doi.org/10.1186/s12861-020-00217-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322864/
https://www.ncbi.nlm.nih.gov/pubmed/32594913
http://dx.doi.org/10.1186/s12861-020-00217-1

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