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Melatonin-stimulated MSC-derived exosomes improve diabetic wound healing through regulating macrophage M1 and M2 polarization by targeting the PTEN/AKT pathway

BACKGROUND: After surgery, wound recovery in diabetic patients may be disrupted due to delayed inflammation, which can lead to undesired consequences, and there is currently a lack of effective measures to address this issue. Mesenchymal stem cell (MSC)-derived exosomes (Exo) have been proven to be...

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Detalles Bibliográficos
Autores principales: Liu, Wei, Yu, Muyu, Xie, Dong, Wang, Longqing, Ye, Cheng, Zhu, Qi, Liu, Fang, Yang, Lili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322868/
https://www.ncbi.nlm.nih.gov/pubmed/32600435
http://dx.doi.org/10.1186/s13287-020-01756-x