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miR-1323 suppresses bone mesenchymal stromal cell osteogenesis and fracture healing via inhibiting BMP4/SMAD4 signaling

BACKGROUND: Atrophic non-union fractures show no radiological evidence of callus formation within 3 months of fracture. microRNA dysregulation may underlie the dysfunctional osteogenesis in atrophic non-union fractures. Here, we aimed to analyze miR-1323 expression in human atrophic non-union fractu...

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Detalles Bibliográficos
Autores principales: Xie, Hui, Liu, Ming, Jin, Yaofeng, Lin, Haiqing, Zhang, Yushan, Zheng, Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322887/
https://www.ncbi.nlm.nih.gov/pubmed/32600409
http://dx.doi.org/10.1186/s13018-020-01685-8