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miR-1323 suppresses bone mesenchymal stromal cell osteogenesis and fracture healing via inhibiting BMP4/SMAD4 signaling
BACKGROUND: Atrophic non-union fractures show no radiological evidence of callus formation within 3 months of fracture. microRNA dysregulation may underlie the dysfunctional osteogenesis in atrophic non-union fractures. Here, we aimed to analyze miR-1323 expression in human atrophic non-union fractu...
Autores principales: | Xie, Hui, Liu, Ming, Jin, Yaofeng, Lin, Haiqing, Zhang, Yushan, Zheng, Song |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322887/ https://www.ncbi.nlm.nih.gov/pubmed/32600409 http://dx.doi.org/10.1186/s13018-020-01685-8 |
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