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Pharmacologic inhibition of mTORC1 mimics dietary protein restriction in a mouse model of lactation

BACKGROUND: Understanding the mechanisms of N utilization for lactation can lead to improved requirement estimates and increased efficiency, which modern dairy diets currently fail to maximize. The mechanistic target of rapamycin complex 1 (mTORC1) is a central hub of translation regulation, process...

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Detalles Bibliográficos
Autores principales: Pszczolkowski, Virginia L., Halderson, Steven J., Meyer, Emma J., Lin, Amy, Arriola Apelo, Sebastian I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322913/
https://www.ncbi.nlm.nih.gov/pubmed/32612825
http://dx.doi.org/10.1186/s40104-020-00470-1