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Epithelial vectorial ion transport in cystic fibrosis: Dysfunction, measurement, and pharmacotherapy to target the primary deficit

Cystic fibrosis patients display multi-organ system dysfunction (e.g. pancreas, gastrointestinal tract, and lung) with pathogenesis linked to a failure of Cl(−) secretion from the epithelial surfaces of these organs. If unmanaged, organ dysfunction starts early and patients experience chronic respir...

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Detalles Bibliográficos
Autores principales: Clunes, Lucy A, McMillan-Castanares, Naia, Mehta, Neil, Mesadieu, Afia, Rodriguez, Jorge, Maj, Mary, Clunes, Mark T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7323271/
https://www.ncbi.nlm.nih.gov/pubmed/32637102
http://dx.doi.org/10.1177/2050312120933807