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Epithelial vectorial ion transport in cystic fibrosis: Dysfunction, measurement, and pharmacotherapy to target the primary deficit
Cystic fibrosis patients display multi-organ system dysfunction (e.g. pancreas, gastrointestinal tract, and lung) with pathogenesis linked to a failure of Cl(−) secretion from the epithelial surfaces of these organs. If unmanaged, organ dysfunction starts early and patients experience chronic respir...
Autores principales: | Clunes, Lucy A, McMillan-Castanares, Naia, Mehta, Neil, Mesadieu, Afia, Rodriguez, Jorge, Maj, Mary, Clunes, Mark T |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7323271/ https://www.ncbi.nlm.nih.gov/pubmed/32637102 http://dx.doi.org/10.1177/2050312120933807 |
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