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Loss of death-associated protein kinase 1 in human bone marrow mesenchymal stem cells decreases immunosuppression of CD4+ T cells

OBJECTIVE: To explore the roles of human mesenchymal stem cell (hMSC) death-associated protein kinase 1 (DAPK1) in modulating CD4+ T lymphocyte proliferation. METHODS: Human MSCs and peripheral blood mononuclear cells were isolated and cocultured in vitro for 3 days. Lentiviral-mediated RNA interfer...

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Detalles Bibliográficos
Autores principales: Wang, Shan, Su, Hongjun, Feng, Pei, Deng, Wen, Su, Chunyan, Wu, Yanfeng, Shen, Huiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7323303/
https://www.ncbi.nlm.nih.gov/pubmed/32586165
http://dx.doi.org/10.1177/0300060520933453