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Phenotype instability of hepatocyte-like cells produced by direct reprogramming of mesenchymal stromal cells
BACKGROUND: Hepatocyte-like cells (iHEPs) generated by transcription factor-mediated direct reprogramming of somatic cells have been studied as potential cell sources for the development of novel therapies targeting liver diseases. The mechanisms involved in direct reprogramming, stability after lon...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7323614/ https://www.ncbi.nlm.nih.gov/pubmed/32276654 http://dx.doi.org/10.1186/s13287-020-01665-z |