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Phenotype instability of hepatocyte-like cells produced by direct reprogramming of mesenchymal stromal cells

BACKGROUND: Hepatocyte-like cells (iHEPs) generated by transcription factor-mediated direct reprogramming of somatic cells have been studied as potential cell sources for the development of novel therapies targeting liver diseases. The mechanisms involved in direct reprogramming, stability after lon...

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Detalles Bibliográficos
Autores principales:	Orge, Iasmim Diniz, Gadd, Victoria L., Barouh, Judah Leão, Rossi, Erik Aranha, Carvalho, Rejane Hughes, Smith, Ian, Allahdadi, Kyan James, Paredes, Bruno Diaz, Silva, Daniela Nascimento, Damasceno, Patrícia Kauanna F., Sampaio, Gabriela Louise, Forbes, Stuart J., Soares, Milena Botelho Pereira, Souza, Bruno Solano de Freitas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7323614/ https://www.ncbi.nlm.nih.gov/pubmed/32276654 http://dx.doi.org/10.1186/s13287-020-01665-z

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