Cargando…
Conformational heterogeneity of Savinase from NMR, HDX-MS and X-ray diffraction analysis
BACKGROUND: Several examples have emerged of enzymes where slow conformational changes are of key importance for function and where low populated conformations in the resting enzyme resemble the conformations of intermediate states in the catalytic process. Previous work on the subtilisin protease,...
| Autores principales: | , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
PeerJ Inc.
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7323712/ https://www.ncbi.nlm.nih.gov/pubmed/32617193 http://dx.doi.org/10.7717/peerj.9408 |