Hybrid Gene Origination Creates Human-Virus Chimeric Proteins during Infection

RNA viruses are a major human health threat. The life cycles of many highly pathogenic RNA viruses like influenza A virus (IAV) and Lassa virus depends on host mRNA, because viral polymerases cleave 5′-m7G-capped host transcripts to prime viral mRNA synthesis (“cap-snatching”). We hypothesized that...

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Detalles Bibliográficos
Autores principales: Ho, Jessica Sook Yuin, Angel, Matthew, Ma, Yixuan, Sloan, Elizabeth, Wang, Guojun, Martinez-Romero, Carles, Alenquer, Marta, Roudko, Vladimir, Chung, Liliane, Zheng, Simin, Chang, Max, Fstkchyan, Yesai, Clohisey, Sara, Dinan, Adam M., Gibbs, James, Gifford, Robert, Shen, Rong, Gu, Quan, Irigoyen, Nerea, Campisi, Laura, Huang, Cheng, Zhao, Nan, Jones, Joshua D., van Knippenberg, Ingeborg, Zhu, Zeyu, Moshkina, Natasha, Meyer, Léa, Noel, Justine, Peralta, Zuleyma, Rezelj, Veronica, Kaake, Robyn, Rosenberg, Brad, Wang, Bo, Wei, Jiajie, Paessler, Slobodan, Wise, Helen M., Johnson, Jeffrey, Vannini, Alessandro, Amorim, Maria João, Baillie, J. Kenneth, Miraldi, Emily R., Benner, Christopher, Brierley, Ian, Digard, Paul, Łuksza, Marta, Firth, Andrew E., Krogan, Nevan, Greenbaum, Benjamin D., MacLeod, Megan K., van Bakel, Harm, Garcìa-Sastre, Adolfo, Yewdell, Jonathan W., Hutchinson, Edward, Marazzi, Ivan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7323901/
https://www.ncbi.nlm.nih.gov/pubmed/32559462
http://dx.doi.org/10.1016/j.cell.2020.05.035

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7323901/
https://www.ncbi.nlm.nih.gov/pubmed/32559462
http://dx.doi.org/10.1016/j.cell.2020.05.035

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