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TNFα-Mediated Priming of Mesenchymal Stem Cells Enhances Their Neuroprotective Effect on Retinal Ganglion Cells

PURPOSE: To determine whether priming of bone marrow mesenchymal stem cells (MSCs) by signals from injured retina, particularly tumor necrosis factor α (TNFα), increase their exosomes’ neuroprotective efficacy on retinal ganglion cells (RGCs). METHODS: MSCs were primed with retinal cell culture cond...

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Detalles Bibliográficos
Autores principales: Mead, Ben, Chamling, Xitiz, Zack, Donald J., Ahmed, Zubair, Tomarev, Stanislav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7324256/
https://www.ncbi.nlm.nih.gov/pubmed/32031578
http://dx.doi.org/10.1167/iovs.61.2.6