Efficient uptake and retention of iron oxide-based nanoparticles in HeLa cells leads to an effective intracellular delivery of doxorubicin

The purpose of this study was to construct and characterize iron oxide nanoparticles (IONP(CO)) for intracellular delivery of the anthracycline doxorubicin (DOX; IONP(DOX)) in order to induce tumor cell inactivation. More than 80% of the loaded drug was released from IONP(DOX) within 24 h (100% at 7...

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Detalles Bibliográficos
Autores principales: Popescu, R. C., Savu, D., Dorobantu, I., Vasile, B. S., Hosser, H., Boldeiu, A., Temelie, M., Straticiuc, M., Iancu, D. A., Andronescu, E., Wenz, F., Giordano, F. A., Herskind, C., Veldwijk, M. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7324358/
https://www.ncbi.nlm.nih.gov/pubmed/32601333
http://dx.doi.org/10.1038/s41598-020-67207-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7324358/
https://www.ncbi.nlm.nih.gov/pubmed/32601333
http://dx.doi.org/10.1038/s41598-020-67207-y

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