Cargando…

Efficient uptake and retention of iron oxide-based nanoparticles in HeLa cells leads to an effective intracellular delivery of doxorubicin

The purpose of this study was to construct and characterize iron oxide nanoparticles (IONP(CO)) for intracellular delivery of the anthracycline doxorubicin (DOX; IONP(DOX)) in order to induce tumor cell inactivation. More than 80% of the loaded drug was released from IONP(DOX) within 24 h (100% at 7...

Descripción completa

Detalles Bibliográficos
Autores principales:	Popescu, R. C., Savu, D., Dorobantu, I., Vasile, B. S., Hosser, H., Boldeiu, A., Temelie, M., Straticiuc, M., Iancu, D. A., Andronescu, E., Wenz, F., Giordano, F. A., Herskind, C., Veldwijk, M. R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7324358/ https://www.ncbi.nlm.nih.gov/pubmed/32601333 http://dx.doi.org/10.1038/s41598-020-67207-y

Ejemplares similares

Intracellular Delivery of Doxorubicin by Iron Oxide-Based Nano-Constructs Increases Clonogenic Inactivation of Ionizing Radiation in HeLa Cells
por: Popescu, Roxana Cristina, et al.
Publicado: (2021)

Enhanced Internalization of Nanoparticles Following Ionizing Radiation Leads to Mitotic Catastrophe in MG-63 Human Osteosarcoma Cells
por: Popescu, Roxana Cristina, et al.
Publicado: (2020)

Fabrication and Cytotoxicity of Gemcitabine-Functionalized Magnetite Nanoparticles
por: Popescu, Roxana Cristina, et al.
Publicado: (2017)

Doxorubicin Inhibits Phosphatidylserine Decarboxylase and Modifies Mitochondrial Membrane Composition in HeLa Cells
por: Bellance, Nadège, et al.
Publicado: (2020)

The Biological Effect of Large Single Doses: A Possible Role for Non-Targeted Effects in Cell Inactivation
por: Veldwijk, Marlon R., et al.
Publicado: (2014)

Electrolyte Metabolism in HeLa Cells
por: Wickson-ginzburg, Margaret, et al.
Publicado: (1963)

Inhibition of HeLa cell growth by doxorubicin-loaded and tuftsin-conjugated arginate-PEG microparticles
por: Hu, Tianmu, et al.
Publicado: (2017)

Hyperthermia and the heat-shock proteins of HeLa cells.
por: Burdon, R. H., et al.
Publicado: (1982)

Lysophosphatidic acid protects cervical cancer HeLa cells from apoptosis induced by doxorubicin hydrochloride
por: Wang, Xibo, et al.
Publicado: (2022)

Editorial: HeLa Cell Sequela
Publicado: (2013)

The fractured genome of HeLa cells
por: Mittelman, David, et al.
Publicado: (2013)

Nanoparticle-Mediated Drug Delivery of Doxorubicin Induces a Differentiated Clonogenic Inactivation in 3D Tumor Spheroids In Vitro
por: Popescu, Roxana Cristina, et al.
Publicado: (2023)

Autophagy Facilitates Salmonella Replication in HeLa Cells
por: Yu, Hong B., et al.
Publicado: (2014)

Hyperthermia enhances the reactivation of irradiated adenovirus in HeLa cells.
por: Piperakis, S. M., et al.
Publicado: (1984)

Determination of the relationship between doxorubicin resistance and Wnt signaling pathway in HeLa and K562 cell lines
por: Mutlu, Pelin, et al.
Publicado: (2018)

The use of 1H spin echo NMR and HPLC to confirm doxorubicin induced depletion of glutathione in the intact HeLa cell.
por: al-Kabban, M., et al.
Publicado: (1988)

Immunotherapy Combined with Large Fractions of Radiotherapy: Stereotactic Radiosurgery for Brain Metastases—Implications for Intraoperative Radiotherapy after Resection
por: Herskind, Carsten, et al.
Publicado: (2017)

Targeting Cell Cycle Checkpoint Kinases to Overcome Intrinsic Radioresistance in Brain Tumor Cells
por: Vlatkovic, Tijana, et al.
Publicado: (2022)

Changes of AgNORs in HeLa cells during serum starvation.
por: Matsumura, K., et al.
Publicado: (1990)

Microtubule-associated proteins of HeLa cells: heat stability of the 200,000 mol wt HeLa MAPs and detection of the presence of MAP-2 in HeLa cell extracts and cycled microtubules
Publicado: (1982)

Photodynamic Effect of Ni Nanotubes on an HeLa Cell Line
por: Hammad Aziz, Muhammad, et al.
Publicado: (2016)

Attenuation of Zika Virus by Passage in Human HeLa Cells
por: Li, Li, et al.
Publicado: (2019)

On the dynamics of the microfilament system in HeLa cells
por: Blikstad, I, et al.
Publicado: (1982)

Exploring the HeLa Dark Mitochondrial Proteome
por: Marini, Federica, et al.
Publicado: (2020)

Non-homologous End Joining Inhibitor SCR-7 to Exacerbate Low-dose Doxorubicin Cytotoxicity in HeLa Cells
por: Kumar, Ajay, et al.
Publicado: (2017)

Lessons from HeLa Cells: The Ethics and Policy of Biospecimens
por: Beskow, Laura M.
Publicado: (2016)

New type of recovery in HeLa cells exposed to bleomycin.
por: Miyamoto, T., et al.
Publicado: (1984)

The Genomic and Transcriptomic Landscape of a HeLa Cell Line
por: Landry, Jonathan J. M., et al.
Publicado: (2013)

Intermediary Metabolism in HeLa and Human Foetal Liver Cells
por: Bryant, C., et al.
Publicado: (1963)

Biology of high single doses of IORT: RBE, 5 R’s, and other biological aspects
por: Herskind, Carsten, et al.
Publicado: (2017)

Transferrin-modified liposomes triggered with ultrasound to treat HeLa cells
por: AlSawaftah, Nour M., et al.
Publicado: (2021)

Nanocarriers of Fe(3)O(4) as a Novel Method for Delivery of the Antineoplastic Agent Doxorubicin Into HeLa Cells in vitro
por: Xia, Kun-kun, et al.
Publicado: (2019)

The Response of HeLa Cells to Fluorescent NanoDiamond Uptake
por: Hemelaar, Simon R., et al.
Publicado: (2018)

Poly A- Transcripts Expressed in HeLa Cells
por: Wu, Qingfa, et al.
Publicado: (2008)

In vitro polymerization of microtubules from HeLa cells
Publicado: (1978)

Transport and topology of galactosyltransferase in endomembranes of HeLa cells
Publicado: (1983)

Evidence for the autophagy of microinjected proteins in HeLA cells
Publicado: (1977)

HeLa Sequencing and Genomic Privacy: The Next Chapter
por: Andrews, Brenda J., et al.
Publicado: (2013)

Dynamic influence of Rhein lysinate on HeLa cells
por: Liu, Jiang, et al.
Publicado: (2018)

Cellular Effects of Cyclodextrins: Studies on HeLa Cells
por: Rusznyák, Ágnes, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_44lrfeukp9tqjdmpbtb365c82j