Cargando…

Analyzing microglial-associated Aβ in Alzheimer’s disease transgenic mice with a novel mid-domain Aβ-antibody

The mechanisms of amyloid-β (Aβ)-degradation and clearance in Alzheimer’s disease (AD) pathogenesis have been relatively little studied. Short Aβ-fragments form by enzymatic cleavage and alternate amyloid-beta precursor protein (APP)-processing. Here we characterized a novel polyclonal Aβ-antibody r...

Descripción completa

Detalles Bibliográficos
Autores principales: Henjum, Kristi, Årskog, Vibeke, Jendresen, Charlotte B., Fladby, Tormod, Torp, Reidun, Nilsson, Lars N. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7324359/
https://www.ncbi.nlm.nih.gov/pubmed/32601313
http://dx.doi.org/10.1038/s41598-020-67419-2