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Corneal Endothelial Pump Coupling to Lactic Acid Efflux in the Rabbit and Mouse

PURPOSE: Confirm that the corneal endothelial pump uses a lactate-coupled water efflux mechanism. METHODS: Corneal thickness, lactate efflux, and stromal [lactate] were measured in de-epithelialized swollen and nonswollen ex vivo-mounted rabbit corneas perfused with bicarbonate-rich and bicarbonate-...

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Detalles Bibliográficos
Autores principales: Li, Shimin, Kim, Edward, Ogando, Diego G., Bonanno, Joseph A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7324437/
https://www.ncbi.nlm.nih.gov/pubmed/32031579
http://dx.doi.org/10.1167/iovs.61.2.7