Increased Rate of Retinal Pigment Epithelial Cell Migration and Pro-Angiogenic Potential Ensuing From Reduced Cystatin C Expression

PURPOSE: Variant B precursor cysteine protease inhibitor cystatin C, a known recessive risk factor for developing exudative age-related macular degeneration (AMD), presents altered intracellular trafficking and reduced secretion from retinal pigment epithelial (RPE) cells. Because cystatin C inhibit...

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Detalles Bibliográficos
Autores principales: Carlsson, Emil, Supharattanasitthi, Wasu, Jackson, Malcolm, Paraoan, Luminita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2020
Materias:
Biochemistry and Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7324439/
https://www.ncbi.nlm.nih.gov/pubmed/32049341
http://dx.doi.org/10.1167/iovs.61.2.9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7324439/
https://www.ncbi.nlm.nih.gov/pubmed/32049341
http://dx.doi.org/10.1167/iovs.61.2.9

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