Non-native proteins inhibit the ER oxidoreductin 1 (Ero1)–protein disulfide-isomerase relay when protein folding capacity is exceeded

Protein maturation in the endoplasmic reticulum (ER) depends on a fine balance between oxidative protein folding and quality control mechanisms, which together ensure high-capacity export of properly folded proteins from the ER. Oxidative protein folding needs to be regulated to avoid hyperoxidation...

Descripción completa

Detalles Bibliográficos
Autores principales: Moilanen, Antti, Ruddock, Lloyd W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Protein Structure and Folding
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7324491/
https://www.ncbi.nlm.nih.gov/pubmed/32102847
http://dx.doi.org/10.1074/jbc.RA119.011766

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7324491/
https://www.ncbi.nlm.nih.gov/pubmed/32102847
http://dx.doi.org/10.1074/jbc.RA119.011766

Ejemplares similares