Targeting a critical step in fungal hexosamine biosynthesis

Aspergillus fumigatus is a human opportunistic fungal pathogen whose cell wall protects it from the extracellular environment including host defenses. Chitin, an essential component of the fungal cell wall, is synthesized from UDP-GlcNAc produced in the hexosamine biosynthetic pathway. As this pathw...

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Detalles Bibliográficos
Autores principales: Lockhart, Deborah E. A., Stanley, Mathew, Raimi, Olawale G., Robinson, David A., Boldovjakova, Dominika, Squair, Daniel R., Ferenbach, Andrew T., Fang, Wenxia, van Aalten, Daan M. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7324522/
https://www.ncbi.nlm.nih.gov/pubmed/32341126
http://dx.doi.org/10.1074/jbc.RA120.012985

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7324522/
https://www.ncbi.nlm.nih.gov/pubmed/32341126
http://dx.doi.org/10.1074/jbc.RA120.012985

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