PLS3 Mutations Cause Severe Age and Sex-Related Spinal Pathology

Objective: Mutations in the X-chromosomal PLS3-gene, encoding Plastin 3, lead to severe early-onset osteoporosis, suggesting a major role for PLS3 in bone metabolism. However, the consequences of abnormal PLS3 function in bone and other tissues remain incompletely characterized. This study evaluated...

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Detalles Bibliográficos
Autores principales: Mäkitie, Riikka E., Niinimäki, Tuukka, Suo-Palosaari, Maria, Kämpe, Anders, Costantini, Alice, Toiviainen-Salo, Sanna, Niinimäki, Jaakko, Mäkitie, Outi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7324541/
https://www.ncbi.nlm.nih.gov/pubmed/32655496
http://dx.doi.org/10.3389/fendo.2020.00393

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7324541/
https://www.ncbi.nlm.nih.gov/pubmed/32655496
http://dx.doi.org/10.3389/fendo.2020.00393

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