A Novel E2F1-EP300-VMP1 Pathway Mediates Gemcitabine-Induced Autophagy in Pancreatic Cancer Cells Carrying Oncogenic KRAS

Autophagy is an evolutionarily preserved degradation process of cytoplasmic cellular constituents, which participates in cell response to disease. We previously characterized VMP1 (Vacuole Membrane Protein 1) as an essential autophagy related protein that mediates autophagy in pancreatic diseases. W...

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Detalles Bibliográficos
Autores principales: Ropolo, Alejandro, Catrinacio, Cintia, Renna, Felipe Javier, Boggio, Veronica, Orquera, Tamara, Gonzalez, Claudio D., Vaccaro, Maria I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7324546/
https://www.ncbi.nlm.nih.gov/pubmed/32655498
http://dx.doi.org/10.3389/fendo.2020.00411

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7324546/
https://www.ncbi.nlm.nih.gov/pubmed/32655498
http://dx.doi.org/10.3389/fendo.2020.00411

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