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A Novel E2F1-EP300-VMP1 Pathway Mediates Gemcitabine-Induced Autophagy in Pancreatic Cancer Cells Carrying Oncogenic KRAS
Autophagy is an evolutionarily preserved degradation process of cytoplasmic cellular constituents, which participates in cell response to disease. We previously characterized VMP1 (Vacuole Membrane Protein 1) as an essential autophagy related protein that mediates autophagy in pancreatic diseases. W...
Autores principales: | Ropolo, Alejandro, Catrinacio, Cintia, Renna, Felipe Javier, Boggio, Veronica, Orquera, Tamara, Gonzalez, Claudio D., Vaccaro, Maria I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7324546/ https://www.ncbi.nlm.nih.gov/pubmed/32655498 http://dx.doi.org/10.3389/fendo.2020.00411 |
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