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Computational translation of drug effects from animal experiments to human ventricular myocytes

Using animal cells and tissues as precise measuring devices for developing new drugs presents a long-standing challenge for the pharmaceutical industry. Despite the very significant resources that continue to be dedicated to animal testing of new compounds, only qualitative results can be obtained....

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Detalles Bibliográficos
Autores principales: Tveito, Aslak, Jæger, Karoline Horgmo, Maleckar, Mary M., Giles, Wayne R., Wall, Samuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7324560/
https://www.ncbi.nlm.nih.gov/pubmed/32601303
http://dx.doi.org/10.1038/s41598-020-66910-0