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Differential expression of polyamine biosynthetic pathways in skin lesions and in plasma reveals distinct profiles in diffuse cutaneous leishmaniasis

Tegumentary leishmaniasis (TL) is a parasitic disease that can result in wide spectrum clinical manifestations. It is necessary to understand host and parasite determinants of clinical outcomes to identify novel therapeutic targets. Previous studies have indicated that the polyamine biosynthetic pat...

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Detalles Bibliográficos
Autores principales: Malta-Santos, Hayna, França-Costa, Jaqueline, Macedo, Amanda, Queiroz, Artur T. L., Fukutani, Kiyoshi F., Muxel, Sandra Marcia, Khouri, Ricardo, Van Weyenbergh, Johan, Boaventura, Viviane, Barral, Aldina, Costa, Jackson M., Floh, Eny Iochevet Segal, Andrade, Bruno B., Floeter-Winter, Lucile M., Borges, Valéria M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7324605/
https://www.ncbi.nlm.nih.gov/pubmed/32601369
http://dx.doi.org/10.1038/s41598-020-67432-5