Rank Order of Small Molecule Induced Hypoxiamimesis to Prevent Retinopathy of Prematurity

Here we rank order small molecule inhibitors of hypoxia inducible factor (HIF) prolyl hydroxylases (PHDs) using severity of oxygen induced retinopathy (OIR) as an outcome measure. Dose response analyses in cell cultures of hepatoma (Hep3B), retinal Müller cells (MIO-M1) and primary retinal endotheli...

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Detalles Bibliográficos
Autores principales: Hoppe, George, Bolok, Youstina, McCollum, Leah, Zhang, Jin, Sears, Jonathan E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7324656/
https://www.ncbi.nlm.nih.gov/pubmed/32656210
http://dx.doi.org/10.3389/fcell.2020.00488

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7324656/
https://www.ncbi.nlm.nih.gov/pubmed/32656210
http://dx.doi.org/10.3389/fcell.2020.00488

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