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Rank Order of Small Molecule Induced Hypoxiamimesis to Prevent Retinopathy of Prematurity
Here we rank order small molecule inhibitors of hypoxia inducible factor (HIF) prolyl hydroxylases (PHDs) using severity of oxygen induced retinopathy (OIR) as an outcome measure. Dose response analyses in cell cultures of hepatoma (Hep3B), retinal Müller cells (MIO-M1) and primary retinal endotheli...
Autores principales: | Hoppe, George, Bolok, Youstina, McCollum, Leah, Zhang, Jin, Sears, Jonathan E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7324656/ https://www.ncbi.nlm.nih.gov/pubmed/32656210 http://dx.doi.org/10.3389/fcell.2020.00488 |
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