Cargando…

Longitudinal Intravital Microscopy Reveals Axon Degeneration Concomitant With Inflammatory Cell Infiltration in an LPC Model of Demyelination

Demyelination and axon degeneration are major events in all neurodegenerative diseases, including multiple sclerosis. Intoxication of oligodendrocytes with lysophosphatidylcholine (LPC) is often used as a selective model of focal and reversible demyelination thought to have no incidence for neurons....

Descripción completa

Detalles Bibliográficos
Autores principales: El Waly, Bilal, Buttigieg, Emeline, Karakus, Cem, Brustlein, Sophie, Debarbieux, Franck
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7324938/
https://www.ncbi.nlm.nih.gov/pubmed/32655371
http://dx.doi.org/10.3389/fncel.2020.00165