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Longitudinal Intravital Microscopy Reveals Axon Degeneration Concomitant With Inflammatory Cell Infiltration in an LPC Model of Demyelination
Demyelination and axon degeneration are major events in all neurodegenerative diseases, including multiple sclerosis. Intoxication of oligodendrocytes with lysophosphatidylcholine (LPC) is often used as a selective model of focal and reversible demyelination thought to have no incidence for neurons....
Autores principales: | El Waly, Bilal, Buttigieg, Emeline, Karakus, Cem, Brustlein, Sophie, Debarbieux, Franck |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7324938/ https://www.ncbi.nlm.nih.gov/pubmed/32655371 http://dx.doi.org/10.3389/fncel.2020.00165 |
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