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Cytotoxicity study of the interleukin-12-expressing recombinant Newcastle disease virus strain, rAF-IL12, towards CT26 colon cancer cells in vitro and in vivo

BACKGROUND: Oncolytic viruses have emerged as an alternative therapeutic modality for cancer as they can replicate specifically in tumour cells and induce toxic effects leading to apoptosis. Despite the great potentials and promising results shown in multiple studies, it appears that their efficacy...

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Detalles Bibliográficos
Autores principales: Najmuddin, Syed Umar Faruq Syed, Amin, Zahiah Mohamed, Tan, Sheau Wei, Yeap, Swee Keong, Kalyanasundram, Jeevanathan, Ani, Muhamad Alhapis Che, Veerakumarasivam, Abhimanyu, Chan, Soon Choy, Chia, Suet Lin, Yusoff, Khatijah, Alitheen, Noorjahan Banu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7325054/
https://www.ncbi.nlm.nih.gov/pubmed/32612457
http://dx.doi.org/10.1186/s12935-020-01372-y