Phosphatidic acid-dependent localization and basal de-phosphorylation of RA-GEFs regulate lymphocyte trafficking

BACKGROUND: Lymphocytes circulate between peripheral lymphoid tissues via blood and lymphatic systems, and chemokine-induced migration is important in trafficking lymphocytes to distant sites. The small GTPase Rap1 is important in mediating lymphocyte motility, and Rap1-GEFs are involved in chemokin...

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Detalles Bibliográficos
Autores principales: Ishihara, Sayaka, Sato, Tsuyoshi, Du, Guangwei, Guardavaccaro, Daniele, Nakajima, Akihiko, Sawai, Satoshi, Kataoka, Tohru, Katagiri, Koko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7325102/
https://www.ncbi.nlm.nih.gov/pubmed/32600317
http://dx.doi.org/10.1186/s12915-020-00809-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7325102/
https://www.ncbi.nlm.nih.gov/pubmed/32600317
http://dx.doi.org/10.1186/s12915-020-00809-0

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