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Combination of TLR agonist and miR146a mimics attenuates ovalbumin-induced asthma

BACKGROUND: microRNA-146a has been reported to be a regulator in the process of attenuating asthma by inhibiting Toll-like receptor 2 (TLR2) pathway. This study aimed to investigate how miR146a-inhibitor affect the symptom of asthma and the underlying mechanisms. METHODS: Ovalbumin (OVA)-induced all...

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Detalles Bibliográficos
Autores principales: Wang, Xinhua, Lu, Xiaoxian, Ma, Chenhui, Ma, Lihong, Han, Shuguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7325265/
https://www.ncbi.nlm.nih.gov/pubmed/32600285
http://dx.doi.org/10.1186/s10020-020-00191-1