Initial seronegative immune-mediated necrotising myopathy with subsequent anti-HMGCR antibody development and response to rituximab: case report

BACKGROUND: Immune-mediated necrotising myopathy (IMNM) is characterised by severe muscle weakness and necrosis with a paucity of inflammation on muscle biopsy. Around 60% of cases are associated with antibodies to the signal recognition particle (SRP) or 3-hydroxy-3-methylglutaryl-coenzyme A reduct...

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Detalles Bibliográficos
Autores principales: Thomas, Rhys, Yeoh, Su-Ann, Berkeley, Rupert, Woods, Andrew, Stevens, Mike, Marino, Silvia, Radunovic, Aleksandar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7325302/
https://www.ncbi.nlm.nih.gov/pubmed/32613157
http://dx.doi.org/10.1186/s41927-020-00128-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7325302/
https://www.ncbi.nlm.nih.gov/pubmed/32613157
http://dx.doi.org/10.1186/s41927-020-00128-5

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