A Model‐Informed Drug Discovery and Development Strategy for the Novel Glucose‐Responsive Insulin MK‐2640 Enabled Rapid Decision Making

A model‐informed drug discovery and development strategy played a key role in the novel glucose‐responsive insulin MK‐2640’s early clinical development strategy and supported a novel clinical trial paradigm to assess glucose responsiveness. The development and application of in silico modeling appro...

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Detalles Bibliográficos
Autores principales: Visser, Sandra A.G., Kandala, Bhargava, Fancourt, Craig, Krug, Alexander W., Cho, Carolyn R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Tutorial
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7325312/
https://www.ncbi.nlm.nih.gov/pubmed/31889297
http://dx.doi.org/10.1002/cpt.1729

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7325312/
https://www.ncbi.nlm.nih.gov/pubmed/31889297
http://dx.doi.org/10.1002/cpt.1729

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