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BDH2 triggers ROS-induced cell death and autophagy by promoting Nrf2 ubiquitination in gastric cancer

BACKGROUND: 3-Hydroxy butyrate dehydrogenase 2 (BDH2) is a short-chain dehydrogenase/reductase family member that plays a key role in the development and pathogenesis of human cancers. However, the role of BDH2 in gastric cancer (GC) remains largely unclear. Our study aimed to ascertain the regulato...

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Detalles Bibliográficos
Autores principales: Liu, Jia-Zhou, Hu, Yi-Lin, Feng, Ying, Jiang, Yun, Guo, Yi-Bing, Liu, Yi-Fei, Chen, Xi, Yang, Jun-Ling, Chen, Yu-yan, Mao, Qin-Sheng, Xue, Wan-Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7325376/
https://www.ncbi.nlm.nih.gov/pubmed/32605589
http://dx.doi.org/10.1186/s13046-020-01620-z