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BDH2 triggers ROS-induced cell death and autophagy by promoting Nrf2 ubiquitination in gastric cancer
BACKGROUND: 3-Hydroxy butyrate dehydrogenase 2 (BDH2) is a short-chain dehydrogenase/reductase family member that plays a key role in the development and pathogenesis of human cancers. However, the role of BDH2 in gastric cancer (GC) remains largely unclear. Our study aimed to ascertain the regulato...
Autores principales: | Liu, Jia-Zhou, Hu, Yi-Lin, Feng, Ying, Jiang, Yun, Guo, Yi-Bing, Liu, Yi-Fei, Chen, Xi, Yang, Jun-Ling, Chen, Yu-yan, Mao, Qin-Sheng, Xue, Wan-Jiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7325376/ https://www.ncbi.nlm.nih.gov/pubmed/32605589 http://dx.doi.org/10.1186/s13046-020-01620-z |
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