Suppression of Inflammasome Activation by IRF8 and IRF4 in cDCs Is Critical for T Cell Priming

Inflammasome activation leads to pyroptotic cell death, thereby eliminating the replicative niche of virulent pathogens. Although inflammasome-associated cytokines IL-1β and IL-18 have an established role in T cell function, whether inflammasome activation in dendritic cells (DCs) is critical for T...

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Detalles Bibliográficos
Autores principales: McDaniel, Margaret M., Kottyan, Leah C., Singh, Harinder, Pasare, Chandrashekhar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7325595/
https://www.ncbi.nlm.nih.gov/pubmed/32375053
http://dx.doi.org/10.1016/j.celrep.2020.107604

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7325595/
https://www.ncbi.nlm.nih.gov/pubmed/32375053
http://dx.doi.org/10.1016/j.celrep.2020.107604

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