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Epithelial Membrane Protein 2 (EMP2) Promotes VEGF-Induced Pathological Neovascularization in Murine Oxygen-Induced Retinopathy

PURPOSE: Retinopathy of prematurity (ROP) is a leading cause of childhood blindness. ROP occurs as a consequence of postnatal hyperoxia exposure in premature infants, resulting in vasoproliferation in the retina. The tetraspan protein epithelial membrane protein-2 (EMP2) is highly expressed in the r...

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Detalles Bibliográficos
Autores principales: Sun, Michel, Wadehra, Madhuri, Casero, David, Lin, Meng-Chin, Aguirre, Brian, Parikh, Sachin, Matynia, Anna, Gordon, Lynn, Chu, Alison
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7325623/
https://www.ncbi.nlm.nih.gov/pubmed/32031575
http://dx.doi.org/10.1167/iovs.61.2.3