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Targeting Parasite-Produced Macrophage Migration Inhibitory Factor as an Antivirulence Strategy With Antibiotic–Antibody Combination to Reduce Tissue Damage

Targeting virulence factors represents a promising alternative approach to antimicrobial therapy, through the inhibition of pathogenic pathways that result in host tissue damage. Yet, virulence inhibition remains an understudied area in parasitology. Several medically important protozoan parasites s...

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Detalles Bibliográficos
Autores principales: Ghosh, Swagata, Padalia, Jay, Ngobeni, Renay, Abendroth, Jan, Farr, Laura, Shirley, Debbie-Ann, Edwards, Thomas, Moonah, Shannon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7325720/
https://www.ncbi.nlm.nih.gov/pubmed/31677380
http://dx.doi.org/10.1093/infdis/jiz579