Internalization and Intoxication of Human Macrophages by the Active Subunit of the Aggregatibacter actinomycetemcomitans Cytolethal Distending Toxin Is Dependent Upon Cellugyrin (Synaptogyrin-2)

The Aggregatibacter actinomycetemcomitans cytolethal distending toxin (Cdt) is a heterotrimeric AB(2) toxin capable of inducing cell cycle arrest and apoptosis in lymphocytes and other cell types. Recently, we have demonstrated that human macrophages are resistant to Cdt-induced apoptosis but are su...

Descripción completa

Detalles Bibliográficos
Autores principales: Boesze-Battaglia, Kathleen, Dhingra, Anuradha, Walker, Lisa M., Zekavat, Ali, Shenker, Bruce J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7325893/
https://www.ncbi.nlm.nih.gov/pubmed/32655562
http://dx.doi.org/10.3389/fimmu.2020.01262

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7325893/
https://www.ncbi.nlm.nih.gov/pubmed/32655562
http://dx.doi.org/10.3389/fimmu.2020.01262

Ejemplares similares