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DMD Pluripotent Stem Cell Derived Cardiac Cells Recapitulate in vitro Human Cardiac Pathophysiology

Duchenne muscular dystrophy (DMD) is a severe genetic disorder characterized by the lack of functional dystrophin. DMD is associated with progressive dilated cardiomyopathy, eventually leading to heart failure as the main cause of death in DMD patients. Although several molecular mechanisms leading...

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Detalles Bibliográficos
Autores principales: Jelinkova, Sarka, Vilotic, Aleksandra, Pribyl, Jan, Aimond, Franck, Salykin, Anton, Acimovic, Ivana, Pesl, Martin, Caluori, Guido, Klimovic, Simon, Urban, Tomas, Dobrovolna, Hana, Soska, Vladimir, Skladal, Petr, Lacampagne, Alain, Dvorak, Petr, Meli, Albano C., Rotrekl, Vladimir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7325914/
https://www.ncbi.nlm.nih.gov/pubmed/32656189
http://dx.doi.org/10.3389/fbioe.2020.00535