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Influence of Polymorphisms Involved in Platelet Activation and Inflammatory Response on Aspirin-Related Upper Gastrointestinal Bleeding: A Case-Control Study

BACKGROUND: Despite the wide benefits of aspirin and its cost-effectiveness, aspirin prescriptions have been reduced due to idiosyncratic responses in susceptible individuals. Low-dose aspirin and single-nucleotide polymorphisms (SNPs) are independently associated with increased risk of gastrointest...

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Detalles Bibliográficos
Autores principales: Mallah, Narmeen, Zapata-Cachafeiro, Maruxa, Aguirre, Carmelo, Ibarra-García, Eguzkiñe, Palacios–Zabalza, Itziar, Macías-García, Fernando, Domínguez-Muñoz, J. Enrique, Piñeiro-Lamas, María, Ibáñez, Luisa, Vidal, Xavier, Vendrell, Lourdes, Martin-Arias, Luis, Sáinz-Gil, María, Velasco-González, Verónica, Figueiras, Adolfo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7325915/
https://www.ncbi.nlm.nih.gov/pubmed/32655394
http://dx.doi.org/10.3389/fphar.2020.00860