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When Stiffness Matters: Mechanosensing in Heart Development and Disease

During embryonic morphogenesis, the heart undergoes a complex series of cellular phenotypic maturations (e.g., transition of myocytes from proliferative to quiescent or maturation of the contractile apparatus), and this involves stiffening of the extracellular matrix (ECM) acting in concert with mor...

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Detalles Bibliográficos
Autores principales: Gaetani, Roberto, Zizzi, Eric Adriano, Deriu, Marco Agostino, Morbiducci, Umberto, Pesce, Maurizio, Messina, Elisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7326078/
https://www.ncbi.nlm.nih.gov/pubmed/32671058
http://dx.doi.org/10.3389/fcell.2020.00334