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Long-Term Exposure of Early-Transformed Human Mammary Cells to Low Doses of Benzo[a]pyrene and/or Bisphenol A Enhances Their Cancerous Phenotype via an AhR/GPR30 Interplay

It is of utmost importance to decipher the role of chronic exposure to low doses of environmental carcinogens on breast cancer progression. The early-transformed triple-negative human mammary MCF10AT1 cells were chronically (60 days) exposed to low doses (10(−10) M) of Benzo[a]pyrene (B[a]P), a geno...

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Detalles Bibliográficos
Autores principales: Donini, Caterina F., El Helou, Myriam, Wierinckx, Anne, Győrffy, Balázs, Aires, Sophie, Escande, Aurélie, Croze, Séverine, Clezardin, Philippe, Lachuer, Joël, Diab-Assaf, Mona, Ghayad, Sandra E., Fervers, Béatrice, Cavaillès, Vincent, Maguer-Satta, Véronique, Cohen, Pascale A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7326103/
https://www.ncbi.nlm.nih.gov/pubmed/32670863
http://dx.doi.org/10.3389/fonc.2020.00712