Cargando…
Long-Term Exposure of Early-Transformed Human Mammary Cells to Low Doses of Benzo[a]pyrene and/or Bisphenol A Enhances Their Cancerous Phenotype via an AhR/GPR30 Interplay
It is of utmost importance to decipher the role of chronic exposure to low doses of environmental carcinogens on breast cancer progression. The early-transformed triple-negative human mammary MCF10AT1 cells were chronically (60 days) exposed to low doses (10(−10) M) of Benzo[a]pyrene (B[a]P), a geno...
Autores principales: | Donini, Caterina F., El Helou, Myriam, Wierinckx, Anne, Győrffy, Balázs, Aires, Sophie, Escande, Aurélie, Croze, Séverine, Clezardin, Philippe, Lachuer, Joël, Diab-Assaf, Mona, Ghayad, Sandra E., Fervers, Béatrice, Cavaillès, Vincent, Maguer-Satta, Véronique, Cohen, Pascale A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7326103/ https://www.ncbi.nlm.nih.gov/pubmed/32670863 http://dx.doi.org/10.3389/fonc.2020.00712 |
Ejemplares similares
-
The Landscape of AhR Regulators and Coregulators to Fine-Tune AhR Functions
por: Gargaro, Marco, et al.
Publicado: (2021) -
Long-term exposure to bisphenol A or benzo(a)pyrene alters the fate of human mammary epithelial stem cells in response to BMP2 and BMP4, by pre-activating BMP signaling
por: Clément, Flora, et al.
Publicado: (2017) -
Tumor-Suppressive Functions of the Aryl Hydrocarbon Receptor (AhR) and AhR as a Therapeutic Target in Cancer
por: Elson, Daniel J., et al.
Publicado: (2023) -
Serotonin Modulates AhR Activation by Interfering with CYP1A1-Mediated Clearance of AhR Ligands
por: Manzella, Christopher R., et al.
Publicado: (2020) -
Exploring the Significance of the Exon 4-Skipping Isoform of the ZNF217 Oncogene in Breast Cancer
por: Bellanger, Aurélie, et al.
Publicado: (2021)