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Application of Fused Organoid Models to Study Human Brain Development and Neural Disorders

Human brain organoids cultured from human pluripotent stem cells provide a promising platform to recapitulate histological features of the human brain and model neural disorders. However, unlike animal models, brain organoids lack a reproducible topographic organization, which limits their applicati...

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Detalles Bibliográficos
Autores principales: Chen, Augustin, Guo, Zhenming, Fang, Lipao, Bian, Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7326106/
https://www.ncbi.nlm.nih.gov/pubmed/32670022
http://dx.doi.org/10.3389/fncel.2020.00133