LC-MS-Based Metabolomic Study of Oleanolic Acid-Induced Hepatotoxicity in Mice

Oleanolic acid (OA), a natural triterpenoid, which has the development prospects in anti-tumor therapy is a widely used hepatoprotective drug in China. It has been reported that OA can cause liver toxicity after higher doses or longer-term use. Therefore, the study aims to explore the possible hepat...

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Detalles Bibliográficos
Autores principales: Feng, Hong, Wu, Ying-Qiu, Xu, Ya-Sha, Wang, Ke-Xin, Qin, Xue-Mei, Lu, Yuan-Fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7326119/
https://www.ncbi.nlm.nih.gov/pubmed/32670053
http://dx.doi.org/10.3389/fphar.2020.00747

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7326119/
https://www.ncbi.nlm.nih.gov/pubmed/32670053
http://dx.doi.org/10.3389/fphar.2020.00747

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