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Integrated Process for Capture and Purification of Virus-Like Particles: Enhancing Process Performance by Cross-Flow Filtration

Virus-like particles (VLPs) are emerging nanoscale protein assemblies applied as prophylactic vaccines and in development as therapeutic vaccines or cargo delivery systems. Downstream processing (DSP) of VLPs comes both with challenges and opportunities, depending on the complexity and size of the s...

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Detalles Bibliográficos
Autores principales: Hillebrandt, Nils, Vormittag, Philipp, Bluthardt, Nicolai, Dietrich, Annabelle, Hubbuch, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7326125/
https://www.ncbi.nlm.nih.gov/pubmed/32671023
http://dx.doi.org/10.3389/fbioe.2020.00489